An implantable epiretinal device for near-infrared light perception
Human vision relies on photoreceptor cells in the outer retina that are sensitive to visible light. However, many people suffer from blindness due to retinal diseases that cause photoreceptor degeneration. Electrical sti...
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Liquid metal based three-dimensional microelectrode arrays integrated with implantable ultrathin retinal prosthesis for vision restoration
Electronic retinal prostheses for stimulating retinal neurons are promising for vision restoration. However, the rigid electrodes of conventional retinal implants can inflict damage on the soft retina tissue. They also ...
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AI-driven tripartite classification for optimizing wearable bioelectronics in depression management
Current disease-sensing devices primarily focus on distinguishing between healthy and diseased states, effective for diagnosis but limited in guiding optimal intervention timing for prevention. We developed a tripartite ...
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Smart contact lens-trained digital twin for device-free personalized uric acid prediction
Tears contain valuable biomarkers and offer potential for noninvasive disease monitoring. However, the lack of correlation analysis between serum uric acid (SUA) and tear uric acid (TUA) has limited their clinical applic...
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In-depth correlation analysis between tear glucose and blood glucose using a wireless smart contact lens
Tears have emerged as a promising alternative to blood for diagnosing diabetes. Despite increasing attempts to measure tear glucose using smart contact lenses, the controversy surrounding the correlation between tear glu...
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In-vivo integration of soft neural probes through high-resolution printing of liquid electronics on the cranium
Current soft neural probes are still operated by bulky, rigid electronics mounted to a body, which deteriorate the integrity of the device to biological systems and restrict the free behavior of a subject. We report a so...
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Magnetically reshapable 3D multi-electrode arrays of liquid metals for electrophysiological analysis of brain organoids
To comprehend the volumetric neural connectivity of a brain organoid, it is crucial to monitor the spatiotemporal electrophysiological signals within the organoid, known as intra-organoid signals. However, previous metho...
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Real-time in vivo monitoring of intraocular pressure distribution in the anterior chamber and vitreous chamber for diagnosis of glaucoma
Glaucoma causes irreversible vision loss due to optic nerve damage and retinal cell degeneration. Since high intraocular pressure (IOP) is a major risk factor for glaucoma development, accurate IOP measurement is crucial...
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Power-integrated, wireless neural recording systems on the cranium using a direct printing method for deep-brain analysis
Conventional power-integrated wireless neural recording devices suffer from bulky, rigid batteries in head-mounted configurations, hindering the precise interpretation of the subject’s natural behaviors. These power so...
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A soft and transparent contact lens for the wireless quantitative monitoring of intraocular pressure
Continuous detection of raised intraocular pressure (IOP) could benefit the monitoring of patients with glaucoma. Current contact lenses with embedded sensors for measuring IOP are rigid, bulky, partially block vision or...
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